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NIFEDIPINE IN MEDICALLY REFRACTORY ANGINA PECTORIS
Author(s) -
Sammel Neville L.,
O'Rourke Michael F.
Publication year - 1981
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1981.tb128320.x
Subject(s) - nifedipine , isosorbide dinitrate , medicine , angina , refractory (planetary science) , cardiology , artery , anesthesia , stable angina , coronary artery disease , calcium , myocardial infarction , physics , astrobiology
Nifedipine was administered to 21 patients with angina pectoris which was refractory to conventional medication. In no case had coronary artery spasm been demonstrated. The condition of 13 patients (62%) improved with nifedipine. and eight patients (38%) had a long‐term response. Nitrate‐type side effects were reported by seven patients (33%), all of whom were being treated concurrently with isosorbide dinitrate. We conclude that nifedipine is a promising drug in the management of angina pectoris, even in the absence of documented coronary spasm.