Premium
EVALUATION OF A NEW BETA‐ADRENERGIC BLOCKING DRUG
Author(s) -
Bett J. H. N.,
Wilkinson R. K.,
Williams J.,
Ryan H.
Publication year - 1980
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1980.tb134573.x
Subject(s) - supine position , blocking (statistics) , drug , beta (programming language) , medicine , crossover study , pharmacology , anesthesia , adrenergic , computer science , pathology , computer network , alternative medicine , programming language , placebo , receptor
The hypotensive effect of penbutolol, a new beta‐adrenergic blocking drug, has been evaluated in a double‐blind crossover trial on 15 patients. Blood pressures were significantly lower during active drug treatment ( P < 0.001), the average reduction being: 1.7/0.9 kPa (13/7 mmHg) supine; 1.5/1.2 kPa (11/9 mmHg) erect.