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DICLOFENAC AND IBUPROFEN IN RHEUMATOID ARTHRITIS AND OSTEOARTHRITIS
Author(s) -
Brooks P. M.,
Hill W.,
Geddes R.
Publication year - 1980
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1980.tb134572.x
Subject(s) - diclofenac , rheumatoid arthritis , medicine , ibuprofen , osteoarthritis , incidence (geometry) , arthritis , crossover study , surgery , anesthesia , pharmacology , placebo , alternative medicine , pathology , physics , optics
Forty patients with arthritis (26 rheumatoid and 14 osteoarthrosis) entered a five‐week double‐blind crossover trial of diclofenac and ibuprofen. Four patients failed to complete the 10‐week trial. There was no statistically significant difference in parameters of disease activity for the rheumatoid arthritis patients, but patients with osteoarthrosis fared significantly better on diclofenac. There was a low incidence of side effects on both regimens.