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INADVERTENT INTRAARTERIAL INJECTION: A PROBLEM OF DRUG ABUSE
Author(s) -
Begg Evan J.,
McGrath Michael A.,
Wade Denis N.
Publication year - 1980
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1980.tb100768.x
Subject(s) - medicine , anesthesia , ischemia , pathophysiology , drug , peripheral , drug injection , surgery , cardiology , pharmacology
Peripheral ischaemia related to the inadvertent intra‐arterial injection of crushed tablets in suspension, was seen in five drug addicts. Characteristic clinical features were observed including pain, discolouration, oedema, immediate and delayed sensory and motor deficits, and pregangrenous and gangrenous changes distal to the site of injection. Definitive treatment remains to be established, but an approach to management, based upon probable pathophysiological mechanisms, is proposed.