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TRIMETHOPRIM/SULPHAMETHOXAZOLE AND DOXYCYCLINE IN ACUTE EXACERBATIONS OF CHRONIC BRONCHITIS IN GENERAL PRACTICE: A COMPARATIVE STUDY
Author(s) -
Pandy G. J.
Publication year - 1979
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1979.tb112073.x
Subject(s) - doxycycline , exacerbation , medicine , chronic bronchitis , bronchitis , trimethoprim , antibiotics , intensive care medicine , microbiology and biotechnology , biology
Fifty‐six patients with acute exacerbation of chronic bronchitis were given one week's treatment either with a combination of trimethoprim and sulphamethoxazole (TMP/SMX) or with doxycycline, in a single blind trial. The study found no significant difference in response to the two treatments, and confirmed that both TMP/SMX and doxycycline are effective and well tolerated agents, which are suitable for the management of acute or chronic bronchitis.