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MEBENDAZOLE THERAPY OF WHIPWORM INFESTATION: A CLINICAL TRIAL
Author(s) -
Pereira Joseph F. V.,
Ghosh Hamendra K.,
Conklin Susan,
Ryan Shirley
Publication year - 1979
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1979.tb112064.x
Subject(s) - mebendazole , regimen , anthelmintic , infestation , medicine , broad spectrum , veterinary medicine , biology , zoology , agronomy , chemistry , combinatorial chemistry
Mebendazole, a new broad‐spectrum oral anthelmintic for nematodes, was given to patients harboring whipworm in a hospital for the mentally retarded. A three‐day regimen (100 mg twice a day) dewormed 75% of the subjects; a five‐day regimen cured 95%. The remaining patients excreted strikingly lesser amounts of the parasites' eggs after therapy. No untoward effects were noted clinically. It is the drug of choice in mixed worm infestations.