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TREATMENT OF INTESTINAL AMOEBIASIS AND GIARDIASIS EFFICACY OF METRONIDAZOLE AND TINIDAZOLE COMPARED
Author(s) -
Welch John S.,
Rowsell Brian J.,
Freeman Cherryl
Publication year - 1978
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1978.tb112560.x
Subject(s) - tinidazole , metronidazole , giardia lamblia , entamoeba histolytica , clearance , amoebiasis , giardia , medicine , intestinal parasite , microbiology and biotechnology , gastroenterology , biology , immunology , antibiotics , helminths , urology
Aboriginal children who were aged from six to nine years and living‐in Cherbourg Community were treated for Giardia lamblia and Entamoeba histolytica infection with either the manufacturer's recommended dose of metronidazole (Flagyl) or with tinidazole (Fasigyn), at two‐dose levels. Tinidazole successfully cleared both protozoans from stools, a single dose being as effective as the longer regimens which were studied. The obvious advantage of single‐dose administration is that it should permit more effective treatment of these intestinal parasites, especially in Aboriginal populations.