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HUMAN INFECTION CAUSED BY PENICILLIN‐INSENSITIVE PNEUMOCOCCI
Author(s) -
Devitt Lorraine,
Riley Ian,
Hansman David
Publication year - 1977
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1977.tb130925.x
Subject(s) - penicillin , cloxacillin , medicine , meningitis , cephalosporin , streptococcus pneumoniae , pneumonia , serotype , microbiology and biotechnology , microgram , pneumococcal pneumonia , antibiotics , pneumococcal infections , pediatrics , virology , biology , in vitro , biochemistry
Three cases of infection, including two fatal ones, caused by pneumococci relatively resistant to penicillin are reported. The patients were a 19‐year‐old New Guinean with fatal multisegmental pneumonia, a 10‐week‐old Caucasian infant who died suddenly from purulent meningitis, and an Australian Aboriginal child aged two years with bronchiectasis complicated by pneumococcal bacteraemia. The pneumococci isolated (serotypes 6, 16 and 19) showed minimal inhibitory concentrations of penicillin G ranging from 0$md1 μg/ml to 1$md0 μg/ml (resistance ratios five to 50) and were also relatively resistant to penicillin V, methicillin, cloxacillin and cephalosporins.