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ANTENATAL DIAGNOSIS OF NEURAL TUBE DEFECTS
Author(s) -
Field Barbara,
Mitchell Gillian,
Kerr Charles
Publication year - 1976
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1976.tb141541.x
Subject(s) - neural tube , obstetrics , amniotic fluid , neural tube defect , medicine , second trimester , reliability (semiconductor) , third trimester , first trimester , tube (container) , pregnancy , gynecology , fetus , biology , materials science , physics , embryo , power (physics) , genetics , quantum mechanics , microbiology and biotechnology , composite material
One hundred women with pregnancies at risk for the recurrence of neural tube defects have entered our monitoring programme of echography and alphafetoprotein estimation (AFP) on amniotic fluid and maternal serum during the second trimester. The results of these pregnancies, the application of the programme, sources of error, and the reliability of alphafetoprotein levels are discussed. Conclusions regarding the value of the tests and routine antenatal screening are made.