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ANALGESICS AND THE KIDNEY A COMMUNITY‐BASED STUDY
Author(s) -
Christie David,
McPherson Lois,
KincaidSmith Priscilla
Publication year - 1976
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1976.tb128207.x
Subject(s) - medicine
The adult population of a small Victorian town was interviewed for current analgesic consumption and the replies were validated by urine testing. One thousand four hundred and fifty‐six subjects were ranked by stated analgesic consumption, and the 50 highest consumers matched for age and sex with non‐consumers. Early morning urine specimens were collected and no significant difference in osmolality or white cell excretion rates was found between the two groups. It was concluded that the absolute risk of renal impairment in chronic analgesic consumers is low, and that patients on therapeutic regimens, including analgesics, may be reassured that any risk is minimal.