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OXPRENOLOL AND HYDRALLAZINE IN THE TREATMENT OF HYPERTENSION
Author(s) -
FREEMAN J. W.,
KNIGHT L. W.
Publication year - 1975
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1975.tb140365.x
Subject(s) - oxprenolol , medicine , methyldopa , pharmacotherapy , hydralazine , anesthesia , blood pressure
Oxprenolol and hydrallazine in combination were found to be as effective as methyldopa in a trial in hypertensive patients. The drugs could be given in a twice‐daily dosage and had a much higher degree of patient acceptance. The side effects of this drug combination were usually due to hydrallazine and were mild and short‐lived, but did require the withdrawal of one patient from the trial. Hydrallazine should be used with caution in the treatment of patients with a history of myocardial ischaemia.