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PROSTAGLANDIN F 2 ɑ GIVEN BY CONTINUOUS TRANSCERVICAL EXTRA‐AMNIOTIC INFUSION COMBINED WITH INTRAVENOUS OXYTOCIN INFUSION FOR THERAPEUTIC TERMINATION OF MID‐TRIMESTER PREGNANCIES
Author(s) -
WALDRON K. W.,
WALTERS W. A. W.
Publication year - 1975
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1975.tb111564.x
Subject(s) - oxytocin , medicine , prostaglandin , therapeutic abortion , misoprostol , pregnancy , abortion , cervix , obstetrics , amniotic fluid , prostaglandins f , anesthesia , fetus , biology , cancer , genetics
Prostaglandin F 2 ɑ was administered by continuous transcervical extra‐amniotic infusion, and supplemented with oxytocin, given intravenously, to induce therapeutic abortion during the second trimester in 50 cases. This method was successful In all cases and has the advantages of being technically simple and requiring 'only a small dose of prostaglandin. The main hazard is intrauterine infection, which can be prevented by preliminary bacteriological investigation of the cervix and appropriate prophylactic antibiotic therapy. Prostaglandins are not yet available in Australia for general medical use. Our experience with prostaglandin F 2 ɑ administered in the manner described indicates that it has an Important part to play in gynaecological therapy.