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LATENT PERNICIOUS ANAEMIA: A PRELIMINARY REPORT
Author(s) -
READING CHRISTOPHER M.
Publication year - 1975
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1975.tb111257.x
Subject(s) - pernicious anaemia , pyridoxine , vitamin b12 , plea , pernicious anemia , medicine , psychosurgery , vitamin b , thiamine , psychiatry , vitamin , pediatrics , anemia , political science , law
Some of the literature describing the psychiatric and neurological symptoms of serum vitamin B12 deficiency without haematological changes is reviewed. Conditions which may be associated with latent pernicious anaemia are mentioned, including those which, if their significance Is missed, can lead to psychosurgery or long‐term hospitalization. A theory linking vitamin deficiency, and possibly deficiencies of other B‐group vitamins, especially B1 (thiamine) and B6 (pyridoxine), with manic‐depressive Illness In some families is proposed. Some factors which may result in latent pernicious anaemia are listed. The suggestion (plea) is made that vitamin B12 deficiency be considered, especially when the response to conventional treatment is poor or continues to fail, and particularly before the Irreversible procedure of psychosurgery Is undertaken.