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ACUTE INTERSTITIAL NEPHRITIS FOLLOWING AMPICILLIN HYPERSENSITIVITY
Author(s) -
Woodroffe A. J.,
Weldon M.,
Meadows R.,
Lawrence J. R.
Publication year - 1975
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1975.tb111234.x
Subject(s) - medicine , interstitial nephritis , ampicillin , prednisolone , nephritis , penicillin , renal biopsy , renal function , hypersensitivity reaction , gastroenterology , antibiotics , kidney , microbiology and biotechnology , biology
A case of acute anuric renal failure following hypersensitivity to ampicillin is presented. Renal biopsy showed severe interstitial nephritis. Treatment with prednisolone and heparin, together with supportive measures and peritoneal dialysis, was followed by rapid recovery of renal function. It Is concluded that hypersensitivity to ampicillin can cause acute interstitial nephritis, analogous to that seen with penicillin and methicillin.