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ANTIBIOTICS, ANTISEPTICS AND TUBERCLE BACILLI
Author(s) -
McDonald P. J.,
Murray C. J.,
McDonald H. M.
Publication year - 1974
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1974.tb93593.x
Subject(s) - bacilli , antimycobacterial , antiseptic , antibiotics , microbiology and biotechnology , medicine , tubercle , bacteria , biology , tuberculosis , mycobacterium tuberculosis , pathology , genetics
The mechanism of antibiotic and antiseptic action is discussed in relation to mycobacteria. Commonly used antituberculosis drugs are shown to act at different sites in the bacterial cell. When planning drug combinations there is a theoretical advantage in choosing drugs which act at different sites. Criteria for resistance are discussed. Several commonly used disinfectants have been tested for antimycobacterial activity; results indicate that phenolics and iodophors are active whilst chlorhexidine has no place as an antimycobacterial agent.