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THE TREATMENT OF PREMATURE LABOUR WITH INTRAVENOUSLY ADMINISTERED SALBUTAMOL
Author(s) -
Korda Andrew R.,
Lyneham Robert C.,
Jones Warren R.
Publication year - 1974
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1974.tb93296.x
Subject(s) - salbutamol , medicine , anesthesia , tachycardia , cervical dilatation , pregnancy , heart rate , pulse rate , side effect (computer science) , blood pressure , stimulant , cervix , asthma , cancer , biology , computer science , genetics , programming language
Salbutamol, a β‐adrenergic stimulant, was administered to 57 patients who were in premature labour. The drug proved to be effective in suppressing uterine activity for a specified period of 24 hours in 94% of the patients treated, excluding four patients in whom treatment was stopped because of other complications. When the membranes were ruptured, 83% of the patients had prolongation of pregnancy for 24 hours or more. Eleven patients with cervical dilatation of 3 cm or more were treated, and only one delivered within 24 hours. The only significant side effects noted were tachycardia and an increased pulse pressure in the mother, and a slight increase in the heart rate in the fetus.