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A CONTROLLED CLINICAL TRIAL OF A NEW ANTIANXIETY AGENT LORAZEPAM (ATIVAN)
Author(s) -
Lawrence Joan M.,
Edwards John E.,
Briggs Geoffrey S.,
Jones Ivor H.
Publication year - 1974
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1974.tb71074.x
Subject(s) - lorazepam , diazepam , anxiety , diazepine , anxiolytic , drug , psychology , medicine , pharmacology , psychiatry , chemistry , ring (chemistry) , organic chemistry
A double‐blind trial of lorazepam (Ativan), a new diazepine, and diazepam (Vailum) an established and widely used diazepine, was undertaken. The two drugs were equally and highly effective in relieving symptoms of anxiety. Both drugs were equally effective for both emotional and physical symptoms of anxiety. Side effects were minimal and no evidence of dependence was found. The drug is considered to be effective and safe and may be expected to be of similar efficiency to existing anxiolytic agents. Study data allowed some comment on the nature of cultural differences In drug response to be made.