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PYRIDOXAL AND FOLATE DEFICIENCY IN ALCOHOLICS
Author(s) -
Davis R. E.,
Smith B. K.
Publication year - 1974
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1974.tb70837.x
Subject(s) - pyridoxal , medicine , vitamin b12 , transaminase , pyridoxine , endocrinology , alkaline phosphatase , liver disease , pyridoxal phosphate , cyanocobalamin , chemistry , biochemistry , enzyme , cofactor
The vitamin B 12 , folate, and pyridoxal status of 50 patients with alcoholism was examined. Twenty‐five had a low serum level of pyridoxal. Fourteen had a reduced level of serum folate and 18 a reduced level of haemoglobin. Eleven patients had a raised vitamin B 12 level and in 10 this was supported by a raised serum level of alkaline phosphatase or glutamic oxaloacetic transaminase suggesting liver disease. There was a significant correlation between a reduced serum pyridoxal and folate level and a significant correlation between a low serum level of pyrodixal and haemoglobin.