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TREATMENT OF PAGET'S DISEASE OF BONE WITH PORCINE CALCITONIN
Author(s) -
Eisman J. A.,
Xipell J. M.,
Sloman J. G.,
Jerums G.,
Martin T. J.
Publication year - 1974
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1974.tb50878.x
Subject(s) - calcitonin , paget's disease of bone , medicine , bone pain , bone remodeling , disease , bone disease , bone histomorphometry , trabecular bone , osteoporosis
Three patients with Paget's disease of bone have been treated for periods of 8 to 18 months with daily injections of porcine calcitonin. In all patients there were substantial decreases in the biochemical indices of increased bone turnover. In two of the patients symptomatic relief of bone pain was obtained, and in one patient there was histological evidence of formation of normal bone after 12 months’ treatment. The possible role of calcitonin in treating Paget's disease is discussed.