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THE SUBCUTANEOUS USE OF HEPARIN IN THE PREVENTION OF VENOUS THROMBOSIS AFTER MYOCARDIAL INFARCTION
Author(s) -
Pitney W. R.,
Pussell B. A.,
Harris Margaret,
Manohar D.
Publication year - 1974
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1974.tb50732.x
Subject(s) - medicine , heparin , venous thrombosis , myocardial infarction , thrombosis , anesthesia , subcutaneous injection , fibrinogen , surgery , cardiology
The 125 I fibrinogen test was used to compare the efficacy of subcutaneous administration of heparin compared to continuous intravenous administration of heparin in the prevention of venous thrombosis after acute myocardial infarction. Heparin was administered subcutaneously in an initial dose of 20,000 to 25,000 units, followed by 10,000 to 12,500 units every 12 hours. Heparin was alternatively administered intravenously by an infusion pump in a dose of 30,000 to 40,000 units per day. Both methods of heparin administration were equally effective in reducing the incidence of venous thrombosis.