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PENTAGASTRIN–STIMULATED GASTRIC ACID SECRETION IN CHOLERA PATIENTS
Author(s) -
Fung Wye–Poh,
Monteiro E. H.,
Tye C. Y.
Publication year - 1973
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1973.tb76507.x
Subject(s) - pentagastrin , cholera , convalescence , achlorhydria , gastric acid , basal (medicine) , medicine , vibrio cholerae , secretion , gastroenterology , bile acid , endocrinology , biology , stomach , virology , bacteria , insulin , genetics
Basal and pentagastrin–stimulated peak acid outputs were determined in 20 male Chinese cholera patients and 20 male Chinese control subjects. The cholera patients were all in convalescence. Statistical analysis showed no significant difference in the mean basal and peak acid outputs between cholera patients and controls. Achlorhydria was present in two of the 20 cholera patients, but in none of the controls; the difference being not statistically significant. It is concluded that the gastric acid secretion of cholera patients is generally not different from that of controls. It is also concluded that cholera does occur in subjects with a normal or even high gastric acid secretion, and that impaired gastric acid production is not an important factor predisposing to infection with Vibrio choleras.