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ULTRASOUND AND CHROMOSOME ABERRATIONS
Author(s) -
Brock R. D.,
Peacock W. J.,
Geard C. R.,
Kossoff G.,
Robinson D. E.
Publication year - 1973
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1973.tb129634.x
Subject(s) - chromosome , ultrasound , mitosis , biology , genetics , medicine , gene , radiology
Human and marsupial whole blood and blood‐ medium mixtures were irradiated with various doses of 2‐25 MHz ultrasound and gamma rays. Doses of ultrasonic irradiation orders of magnitude higher than those used for diagnostic studies produced very few chromosome aberrations. A large proportion of the chromosome aberrations observed were gaps, rather than true breaks. If gaps are excluded from the analysis, our data show no significant induction of chromosome damage by ultrasound. High doses of ultrasound did, however, cause mitotic inhibition. Although very little chromosome damage was observed there is still the possibility of induced genetic damage which is undetectable at a cytological level; consideration of this possibility should be given in clinical applications.