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TOPICAL DRUG ADDICTION: ADVERSE EFFECTS OF FLUORINATED CORTICOSTEROID CREAMS AND OINTMENTS
Author(s) -
BURRY JOHN N.
Publication year - 1973
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1973.tb118065.x
Subject(s) - rosacea , medicine , dermatology , acne , adverse effect , drug , corticosteroid , atrophy , pharmacology , surgery
The adverse effects which the anti‐inflammatory powers of topical fluorinated corticosteroids have on acne rosacea, “seborrhæic” complexions and tinea infection of the skin are illustrated by several cases. These steroids also cause local atrophy, purpura, telangiectasia and ulceration by interfering with skin collagen metabolism. Many patients are afraid to stop using the locally applied steroids because of the uncomfortable rebound inflammation which follows their withdrawal. Both the skin and the patient can therefore become readily “hooked” on these topical drugs.