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PRIMARY HYPERPARATHYROIDISM EXPERIENCES WITH 60 PATIENTS
Author(s) -
PRATLEY STEPHANIE K.,
POSEN SOLOMON,
REEVE THOMAS S.
Publication year - 1973
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1973.tb110473.x
Subject(s) - medicine , pathological , primary hyperparathyroidism , hyperplasia , parathyroidectomy , surgery , adenoma , hyperparathyroidism , thyroid , etiology , parathyroid hormone , calcium
Sixty cases of primary hyperparathyroidism are presented. The patients were selected on the basis of three rigid arbitrary criteria, which included the presence of abnormal parathyroid tissue. Females outnumbered males 3:2, and half the patients were in their fifth and sixth decades. Half the patients presented with urinary calculi, while a further 28% gave a history of calculi. Bone disease was present in at least 35% of patients. Preoperative measures for the localization of tumours were largely unsuccessful. Abnormal tissue was more commonly located at the lower poles of the thyroid than at the upper poles. The pathological diagnoses were hyperplasia in 4 cases, adenoma in 48 cases and adenocarcinoma in 1 case. In the other 7 cases no firm pathological diagnosis was made. Postoperative hypocalcæmia was more common in females than in males. Postoperative hypomagnesaemia was found in 16 of 28 patients with adequate data. Postoperative cardiac problems occurred in five patients, including a girl aged 19 years. Twenty‐eight patients were alive and well 1 to 10 years after parathyroidectomy. Most of the remainder were chronically ill, usually with residual problems. Patients who presented with unrelated symptoms tended to keep these, in spite of the surgical removal of abnormal parathyroid tissue.