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THE USE OF A NEW VASOCONSTRICTOR IN THE MANAGEMENT OF BURNS
Author(s) -
Clarke A Murray,
Solomon John R.,
Keogh E. Julian
Publication year - 1972
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1972.tb47351.x
Subject(s) - vasopressin , eschar , ornithine , medicine , vasoconstrictor agents , anesthesia , arginine , surgery , chemistry , vasoconstriction , biochemistry , amino acid
This report refers to the use of a new vasoconstrictor — ornithine vasopressin (POR8) — with particular reference to the surgical excision of burn eschar. The authors believe that the use of ornithine vasopressin for this purpose has not been reported previously (Sandoz, personal communication, 1971). The advantages and disadvantages in the use of ornithine vasopressin are discussed. Catecholamines, adrenaline and noradrenaline are used in many branches of surgery as vasoconstrictive agents. When ornithine vasopressin is used in conjunction with general anaesthesia, the usual disadvantages of the excision of burn eschar do not occur.