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A CONTROLLED STUDY OF PRINDOLOL (VISKEN) IN HYPERTENSION
Author(s) -
Thorpe Peter
Publication year - 1972
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1972.tb47305.x
Subject(s) - medicine , blocking (statistics) , mechanism (biology) , pharmacology , computer science , philosophy , epistemology , computer network
The mechanism of action of the beta‐adrenergic blocking agents in the management of hypertension has not been fully elucidated. Of a group of 20 patients with varying grades of hypertension treated with prindolol, 18 appeared to respond well, and two not at all. Fourteen of the original group of 20 were submitted to a double‐blind trial. Results were significant in favour of the active agent, and indicate that prindolol is a useful agent in the management of mild to complicated hypertension when used alone.