Premium
THE VALUE OF SERUM THYROTROPHIN MEASUREMENT IN THE DIAGNOSIS AND MANAGEMENT OF HYPOTHYROIDISM
Author(s) -
Burger Henry G.,
Patel Yogesh C.
Publication year - 1972
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1972.tb47302.x
Subject(s) - euthyroid , medicine , thyroid function , endocrinology , thyroid , hormone , thyroid stimulating hormone , radioimmunoassay
The concentration of thyroid‐stimulating hormone (TSH) has been measured in the sera of 94 patients with presumed normal thyroid function and in the sera of 85 patients with primary hypothyroidsism, and a clear‐cut separation of the two groups has been demonstrated, the ranges of concentration being < 0.2‐3.4 μu/mi and 6.8‐1546 μu/ml respectively. TSH levels were elevated in some patients judged euthyroid on standard criteria, and the significance of this observation is discussed. The modal dose of thyroxine to render euthyroid 27 patients with primary hypothyroidism was 0‐2 mg daily, the resulting free thyroxine index being 7.2, TSH 0.13 μ/ml. It is concluded that serum TSH measurements are a valuable adjunct to the diagnosis and management of primary hypothyroidism.