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INTESTINAL MALABSORPTION WITH SUBTOTAL VILLOUS ATROPHY UNRESPONSIVE TO A GLUTEN‐FREE DIET BUT RESPONDING TO IMMUNOSUPPRESSIVE THERAPY
Author(s) -
Hillman H. S.
Publication year - 1972
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1972.tb47159.x
Subject(s) - villous atrophy , malabsorption , azathioprine , gastroenterology , medicine , atrophy , gluten free , sprue , intestinal malabsorption , biopsy , diarrhea , gluten , pathology , coeliac disease , biology , disease , mold , genetics
A patient presenting with clinical and biochemical evidence of malabsorption and a small‐bowel biopsy pattern of subtotal villous atrophy failed to respond to a gluten‐free diet but responded to the adminisstration of corticosteroids. He relapsed after 18 months and then responded again after the addition of azathioprine. The possible mechanism of the villous atrophy and malabsorption is discussed.