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PLATELET LIFE SPAN IN PATIENTS WITH VALVULAR HEART DISEASE AND STARR‐EDWARDS PROSTHESES
Author(s) -
Brodie G. N.,
Firkin B. G.
Publication year - 1972
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1972.tb46872.x
Subject(s) - medicine , platelet , hepatosplenomegaly , cardiology , surgery , red cell , life span , heart disease , disease , gerontology
Platelet survival studies have been carried out before surgery on five patients with severe valvular heart disease. Survival was shortened, and recovery of radioactivity was low in one patient with severe calcific multivalvular disease and hepatosplenomegaly. Platelet survival studies were performed on seven patients with Starr‐Edwards prostheses. All patients had normal survival times. Red‐cell survival, using the 51 Cr technique, was reduced in the five patients studied. Red‐cell fragmentation was a prominent feature of peripheral blood films of these patients. The results suggest that the platelet is not as vulnerable as the red cell to the traumatic forces caused by turbulence in patients with Starr‐Edwards prostheses.