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A NEW BRONCHODILATOR, Th 1165 a (BEROTEC)
Author(s) -
Rebuck A. S.,
Saunders N. A.
Publication year - 1972
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1972.tb46770.x
Subject(s) - bronchodilator , bronchodilator agents , medicine , asthma
The acute response to inhaled Th 1165a in the form of a metered aerosol was tested in 38 patients with asthma. The forced expiratory volume in one second (FEV 1 ) increased in all patients, the mean value rising from 56.7% of predicted value to 71.6% (P < 0.025). A similar rise occurred in vital capacity (65.5% to 78.4%, P < 0.025). As 31 of the patients had inhaled salbutamol or orciprenaline less than four hours before the test, these changes may be considered as additional improvement. It appears that Th 1165a, when used as a test agent for acute airways responsiveness, functions as a powerful bronchodilator.