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THE AUSTRALIAN RIFAMPICIN TRIAL
Author(s) -
Proust Anthony,
Evans Cyril
Publication year - 1972
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1972.tb103596.x
Subject(s) - rifampicin , medicine , tuberculosis , mycobacterium tuberculosis , clinical trial , antibiotics , pharmacology , intensive care medicine , microbiology and biotechnology , pathology , biology
Rifampicin is a new broad‐spectrum antibiotic, active against Mycobacterium tuberculosis and some atypical mycobacteria. An Australian clinical trial of rifampicin was undertaken in June, 1969, and an evaluation of side effects and toxicity and of the effect of rifampicin on hepatic function has already been presented. 4 This paper discusses the protocol of the trial and presents an evaluation of the therapeutic efficacy of rifampicin based on bacteriological conversion.