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THE USE OF CLONIDINE (CATAPRES) IN THE TREATMENT OF HYPERTENSION
Author(s) -
Mathew John Y.,
Parker Michael LeMoine
Publication year - 1971
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1971.tb92741.x
Subject(s) - clonidine , medicine , methyldopa , somnolence , anesthesia , thiazide , pregnancy , blood pressure , adverse effect , biology , genetics
Clonidine is a potent hypotensive agent which is effective in the control of moderate and severe hypertension in patients with essential, malignant and reno‐vascular hypertension. It appears to be free from serious toxicity, and does not produce marked postural hypotension, although it does cause a relatively high incidence of dry mouth and somnolence. Two patients conceived whilst taking clonidine, and one of these continued the drug throughout the pregnancy. Both babies were apparently normal. The hypotensive action of clonidine is potentiated by thiazide diuretics, fruse‐ mide and methyldopa.