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AUTOANTIBODIES IN BULLOUS PEMPHIGOID
Author(s) -
Muller H. K.,
Sutherland R. C.,
Jamieson W. J.,
Boer W. G. K. M.
Publication year - 1971
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1971.tb87630.x
Subject(s) - bullous pemphigoid , autoantibody , basement membrane , epithelium , pemphigoid , stratified squamous epithelium , medicine , pathology , immunology , thyroid , antibody
Immunopathological studies on three cases of bullous pemphigoid are presented. All cases demonstrated humoral IgG specific for the basement membrane zone of stratified squamous epithelium, and in‐vivo binding of IgG and complement in the basement membrane zone of the patients’ skin. In addition, humoral autoantibodies against thyroid elements and gastric parietal cells were detected in two of the patients.