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INTERCITY TRANSFER OF CANINE KIDNEY ALLOGRAFTS
Author(s) -
Sheil A. G. R.,
Hartley L. C. J.,
Clunie G. J. A.,
Rogers J. H.,
Storey B. G.,
Kelly G. E.
Publication year - 1971
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1971.tb87513.x
Subject(s) - medicine , kidney , transplantation , kidney transplantation , surgery , cold ischemia , urology , ischemia , reperfusion injury
Kidneys were removed from dogs, perfused with cold electrolyte solution and transferred by domestic airlines between Brisbane and Sydney in containers surrounded by ice. The transplant team in the respective capitals implanted the kidneys into unrelated recipient dogs. It was found that the minimum total ischæmic interval for the allografts was three and a half hours when the kidneys were prepared for removal before the death of the donor, and four to five hours when operation for kidney removal did not commence until after the death of the donor. The former kidneys worked well after reimplantation, but the majority of the latter showed severe ischæmic changes, and some were irreparably damaged. The total ischæmic intervals involved are acceptable for clinical transplantation.