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CLINICO–PATHOLOGICAL FEATURES IN SEVEN FATAL CASES OF INFLUENZA A2/HONG KONG/68 PNEUMONIA
Author(s) -
Searle J.,
Bryant S.,
Forgan–Smith R.
Publication year - 1971
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1971.tb50673.x
Subject(s) - autopsy , pneumonia , pathological , medicine , pathology , hypoxia (environmental) , viral pneumonia , disease , covid-19 , immunology , infectious disease (medical specialty) , chemistry , oxygen , organic chemistry
The autopsy findings from seven patients who died of primary pneumonia due to influenza A2/Hong Kong/68 are presented. The gross and microscopic appearances due to the pneumonia are described, as well as changes present in other tissues. No association with chronic rheumatic heart disease was found. Five of the seven patients were shown to be markedly hypoxic and the serum levels of three enzymes (SGOT, LDH and SAP) were elevated in all five. It is suggested that the serum enzyme elevations are a result of increased permeability of cell membranes caused by severe systemic hypoxia.