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TREATMENT OF GONORRHOEA BY PENICILLIN AND A RENAL BLOCKING AGENT (PROBENECID)
Author(s) -
Hatos G.
Publication year - 1970
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1970.tb84444.x
Subject(s) - probenecid , penicillin , medicine , procaine , intramuscular injection , ceftriaxone , benzylpenicillin , pharmacology , antibiotics , microbiology and biotechnology , biology
Since 1961, there has been an increase of 53·3% in the number of notified cases of gonorrhoea in New South Wales. The decrease in sensitivity of strains of the gonococcus to penicillin has been world‐wide. At the Sydney clinic, in the first six months of 1969, the failure rate associated with the penicillin treatment used as a routine at this time was 20·35%. In a recent series, 217 males with proved gonococcal urethritis were treated by means of a single intramuscular injection of 2·5 megaunits of procaine penicillin and an orally administered kidney‐blocking agent, probenecid, with a resultant failure rate of 2·76%.