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THE USE OF CONTINUOUS PROGESTOGEN CONTRACEPTION IN THE TREATMENT OF MIGRAINE
Author(s) -
Somerville B. W.,
Caret H. M.
Publication year - 1970
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1970.tb84395.x
Subject(s) - migraine , medicine , progestogen , incidence (geometry) , side effect (computer science) , family planning , obstetrics , gynecology , anesthesia , population , research methodology , hormone , physics , computer science , optics , programming language , environmental health
A small pilot study on the use of the continuous progestogen contraceptive, 3 acetoxychlormadinone (AY 11440) in dosage of 0·8 mg a day, in the prevention of migraine is described. Twenty‐two patients were followed for a mean duration of 4·8 months. The condition of nine patients showed improvement to 50% or better. The incidence of side effects was high, particularly polymenorrhœa and breakthrough bleeding. It is concluded that the benefit of such prophylactic treatment, If any, must be small, and is probably outweighed by the high incidence of side effects. The close relationship between uterine bleeding and migraine in some patients is noted, and the mechanism of this is considered.