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A NEW TYPE OF ORAL CONTRACEPTIVE
Author(s) -
McBride W.
Publication year - 1970
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1970.tb77813.x
Subject(s) - megestrol acetate , medicine , placebo , chlormadinone acetate , megestrol , mestranol , family planning , gynecology , population , research methodology , cancer , environmental health , pathology , alternative medicine
A trial was conducted of a new type of oral contraceptive; 610 women were studied over a period of 46 months, for a total of 13,328 cycles. The therapy consisted of ethinyl œstradiol, 0.1 mg, plus megestrol acetate, 0.1 mg, for 16 days, commencing on the third day of the cycle, followed by ethinyl œstradiol, 0.1 mg, plus megestrol acetate, 1 mg, for seven days; in order to secure regular withdrawal bleeding, five placebo tablets were then taken. Twenty‐eight tablets were taken in each cycle, of which twenty‐three contained active ingredients. No pregnancies occurred and the cycle control was excellent.