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AMYLOIDOSIS IN PAPUA‐NEW GUINEA
Author(s) -
Cooke R. A.,
Champness L. T.
Publication year - 1970
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1970.tb63421.x
Subject(s) - amyloidosis , new guinea , pathology , pathological , amyloid (mycology) , thyroid , spleen , medicine , kidney , disease , ethnology , history
Forty‐seven cases of primary and 50 cases of secondary amyloidosis are reported from Papua‐New Guinea, where this disease appears to be particularly prevalent. The clinico‐pathological features are described. Nephropathy was the commonest manifestation. This was frequently accompanied by an amyloid goitre (particularly in children). Cardiac arrhythmias and steatorrhœa also occurred. Deposition of amyloid was heavy in the kidneys and thyroid, but was slight in the liver, spleen and adrenals, being confined almost entirely to the walls of small vessels in these organs. No involvement of the nervous system was detected, and the ætiology could not be ascribed to any obvious genetic influence.