CYBERNETICS

The purpose of the SPR sensor is to quickly and accurately determine the refractive index of the environment with the ability to diagnose the presence of a specific substance. SPR devices and biosensor diagnostic methods for laboratory diagnostics in medicine, veterinary medicine, determination of environmental pollution, for food quality control are being developed. The work is devoted to the development of devices based on the surface plasmon resonance of the “Plasmontest” series, which can be used for refractometric and biosensor applications. Comparison of optical circuits of SPR devices, their capabilities and operational characteristics during biochemical and physical experiment are carried out Features of the design of devices "Plasmontest" with discrete and aperture optical circuits are presented. The method of approximation of the resonant SPR curve is proposed to accurately find the value of the resonance minimum. Procedures for normalizing and calibration of devices have been developed to improve measurement accuracy. The use of "Plasmontest" devices for refractometry, for the development of thin-film technological processes and for the creation of methods of immunosensory detection of a number of bacteria and toxins is described. Work on the creation of “Plasmontest” series devices has shown the possibility of creating portable SPR devices for refractometric studies, thin film studies and biosensor studies.