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LEUKOCYTE ANTIGENS IN RENAL TRANSPLANTATION 8. SUCCESSFUL RENAL TRANSPLANTATION IN THE PRESENCE OF A POSITIVE CROSS MATCH
Author(s) -
Heale W. F.,
Morris Peter J.,
Bennett R. C.,
Mortensen P. J.,
Ting A.
Publication year - 1969
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1969.tb107152.x
Subject(s) - contraindication , transplantation , medicine , histocompatibility , creatinine , human leukocyte antigen , kidney transplantation , urology , antigen , immunology , pathology , alternative medicine
Renal transplantation in the presence of preformed antibodies against donor histocompatibility antigens (positive cross match) almost inevitably results in immediate failure of the graft. The presence of a positive cross match is considered a contraindication to renal transplantation. A well‐documented case of a successful renal transplant (creatinine clearance of 80 ml/min. at seven months) in the presence of a positive cross‐match is described, but it is nevertheless recommended that a positive cross match should be considered a definite contraindication to transplantation.