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ONE MILLILITRE INJECTIONS OF Rh o (D) IMMUNE GLOBULIN (HUMAN) IN PREVENTION OF Rh IMMUNIZATION A FURTHER REPORT ON THE CLINICAL TRIAL
Author(s) -
Bishop G. J.,
Krieger Vera I.
Publication year - 1969
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1969.tb105689.x
Subject(s) - antibody , abo blood group system , immunization , immune system , medicine , clinical trial , globulin , immunology , gamma globulin , rh blood group system
The final results of a clinical trial of 1 ml injections of Rh o (D) immune globulin (human) (equivalent to 1,200 μ g anti‐D) for a period of some months after delivery are reported. Data in relation to the 11 control mothers who became immunized during the study are also reported. One millilitre of potent Rh o (D) immune globulin (human) injected into Rh negative mothers at risk within 72 hours of delivery of an ABO compatible, Rh positive baby will prevent development of circulating anti‐D antibody in the period of six weeks to six months after the injection when such antibodies usually appear.