Surgery

to be three times more common in males than in females. It is observed that this relative frequency of carcinoma in the sexes corresponds closely to that of chronic peptic ulcer. The age incidence reached a maximum in females'during the fifth decade and in males during the sixth decade. The clinical histories were grouped under various symptom-complex heads. Of those presenting a history suggestive of simple gastric ulcer there were 7*8 per cent., and in these cancer was only diagnosed by microscopic examination. The edge and base of the ulcer showed evidence of early carcinoma in the form of epithelial wandering through basement membrane. Gastric carcinoma which had developed in individuals with long-standing symptoms of peptic ulcer occurred in 47*3 per cent. Only in 3 ] *9 per cent, of the cases were there no