Pathology

The cause of " anaphylaxis," or that susceptibility to repeated injections of serum which can, under certain circumstances, be originated in animals, is not only important from the scientific standpoint but also from its practical bearings, for, from time to time, the phenomenon is seen in cases where sera have been injected in patients for therapeutic purposes. In this connection the recent paper of Briedl and Kraus (JViener medicinisclie Wochenschrift, 18th March 1909) merits attention. These observers studied the phenomenon in dogs which received intravenously doses of horse or ox serum twenty-one days after the sub-