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BIOCHEMISTRY
Author(s) -
Harrapp DeuUsch
Publication year - 1958
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1958.tb86374.x
Subject(s) - citation , computer science , information retrieval , library science
K. REEMTSMA et alii (Surgery, July, 1957) describe a test of pancreatic function based on comparative absorption of fat and fatty acid. They found that patients with" pure" pancreatic deficiency (due to surgical removal of the pancreas, obstruction of the pancreatic duct or fibrous replacement of the pancreas) showed marked impairment of fat absorption but normal fatty acid absorption. Patients with malabsorption due to causes other than pancreatic deficiency (in conditions such as sprue, regional enteritis or intestinal lipodystrophy) showed marked impairment of both fat and fatty acid absorption.. Patients with fibrocystic disease of the pancreas showed a pattern unlike " pure" pancreatic deficiency but similar to the group with malabsorption of non-pancreatic origin. They describe a simplified version of the test based on the percentage of the administered dose present in the bloodstream four hours after ingestion. The test is suggested for clinical use in differential diagnosis of malabsorption states.