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SPONTANEOUS SPINAL SUBARACHNOID HÆMORRHAGE
Author(s) -
R A HENSON,
P B CROFT
Publication year - 1956
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1956.tb56687.x
Subject(s) - citation , computer science , psychology , information retrieval , world wide web
beenestablished. The toxicity appearsto be relatively low and the LD50 is rather more than twice that of acetylsalicylic acid. Prolonged treatment has been found to affect neither the bone marrow function nor the biochemistry of the blood and urine. Absorption after administrationby mouth is rapid; peak plasmalevels are said to be reachedafter one to two hours, and most of the compound is recovered from the urine in a conjugated' form. No aniline or aniline derivative is produced. Various investigatorshave shown that methremoglobinis not produced; aneemia, the depression of bone marrow function, and undesirable effects on the blood clotting mechanismhave not been demonstrated.