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A TEXT‐BOOK OF MIDWIFERY
Author(s) -
Otto Spiegelberg,
Jamieson B. Hurry
Publication year - 1939
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1939.tb115323.x
Subject(s) - citation , computer science , library science
• metastatic deposit, one centimetre in diameter. was present in the right kidney. The right adrenal gland was replaced by a secondary growth, whilst the left contained a metastatic deposit. two centimetres in diameter. Direct infiltration from the lymphatic metastases was seen in the lumbar vertebrre and psoas muscles. In the lungs hypostatic pneumonia was present. The heart had calcified aortic. cusps and coronary arteries. The testicles, bladder, prostate gland. gastro-intestinal system, liver. spleen, pancreas, thyreoid gland, trachea and brain were normal. Microscopic examination of a longitudinal section at the jnnction of normal and malignant mucous membrane reveals on the malignant side undifferentiated cancer cells replacing mucosa and infiltrating the muscle coat, whilst the normal side is largely desquamated except for a few patches of transitional epithelium. The cancer cells are chiefiy about 10", in diameter, with large hyperchromatic nuclei. Microscopic examination of a section through a skin nodule reveals undifferentiated disorderly cells invading the dermis. In a section through a lymph gland the cancer cells are seen to be extensively replacing lymphatic tissue. A section through the metastatic deposit iR the kidney displays similar anaplastic growth.