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THERAPEUTICS
Author(s) -
REYNOLD W. WILCOX
Publication year - 1934
Publication title -
medical journal of australia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 131
eISSN - 1326-5377
pISSN - 0025-729X
DOI - 10.5694/j.1326-5377.1934.tb90980.x
Subject(s) - citation , computer science , information retrieval , library science
Germicidal Action of Holocaine. Holocaine hydrochloride, a body produced by the combination of P ienacetin and paraphenetidin, and occurring in small colourless crystals, ?las been a good deal used in 1 per cent, solution as a local anesthetic ^ operations on the eye. Randolph {Johns Hopldns Hosp. Bull,, -^Itiinore, July 1898) states that he has used it in fifty-four cases Iridectomy, cataract extraction, tenotomies, foreign bodies, etc.), and llnd that as an anesthetic it is as efficient as cocaine. Anaesthesia was Produced in a little over two minutes, and the same number of instillatl0ns> required as when using cocaine. To investigate its alleged ?ci'micidal properties, experiments were made with a 1 per cent, solution various pyogenic organisms, and it was found that it exerts an lnhibitory effect on their growth, and kills them in a period somewhere