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A randomized controlled trial of oxygen therapy for patients who do not respond to upper airway surgery for obstructive sleep apnea
Author(s) -
Simon A. Joosten,
Michael Tan,
AiMing Wong,
Shane A. Landry,
Paul Leong,
Scott A. Sands,
Caroline Beatty,
Luke Thomson,
J Stonehouse,
Anthony Turton,
Garun S. Hamilton,
Bradley A. Edwards
Publication year - 2020
Publication title -
journal of clinical sleep medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.529
H-Index - 92
eISSN - 1550-9397
pISSN - 1550-9389
DOI - 10.5664/jcsm.8920
Subject(s) - medicine , polysomnography , obstructive sleep apnea , placebo , anesthesia , oxygen therapy , apnea , continuous positive airway pressure , randomized controlled trial , sleep apnea , hypopnea , airway , alternative medicine , pathology
We aimed to determine whether patients diagnosed with obstructive sleep apnea (OSA) who fail to respond to upper airway surgery may be successfully treated with supplemental oxygen and whether we could identify baseline physiologic endotypes (ie, collapsibility, loop gain, arousal threshold, and muscle compensation) that predict response to oxygen therapy.

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