Unexpected Finding of Idiopathic REM Sleep Behavior Disorder in a Young Healthy Male With Snoring: A Case Report
Author(s) -
Matthew S. Brock,
Sean Shirley,
Luis Rohena,
Brian A. Moore,
Vincent Mysliwiec
Publication year - 2019
Publication title -
journal of clinical sleep medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.529
H-Index - 92
eISSN - 1550-9397
pISSN - 1550-9389
DOI - 10.5664/jcsm.7938
Subject(s) - sleep medicine , obstructive sleep apnea , medicine , polysomnogram , ambulatory , polysomnography , gerontology , sleep disorder , psychiatry , apnea , surgery , insomnia
Idiopathic rapid eye movement sleep behavior disorder is characterized by vocalizations and complex motor behaviors during sleep. We report a case of a 44-year-old male with a 20-year history of dream enactment behavior that was incidentally captured on a polysomnogram during an evaluation for obstructive sleep apnea. Genetic testing found the patient had a homozygous deletion for one of the five tandem repeats in exon 18 of the PER3 gene. This case highlights a potential genetic basis for idiopathic rapid eye movement sleep behavior disorder.
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